Dr. Wade Mace


E: wade.mace@agresearch.co.nz


BSc MSc PhD (Chemistry) University of Waikato

Research interests & activities

Natural Products Chemistry and Analytical Chemistry specialising in:

  • Development of methods for quantifying novel and bioactive endophyte metabolites using advanced LC-MS/MS techniques
  • Chemical characterisation of novel and bioactive endophyte metabolites
  • Development of rapid screening methods for identifying endophytes of scientific and commercial interest
  • Quantitative assessment of secondary metabolite expression (namely alkaloids) in host/endophyte associations, utilising GC-FID, UHPLC and LC-MS/MS techniques
  • Evaluating performance of novel endophyte/host associations for scientific and commercial development
  • Development of tools to assist in the breeding for the enhancement of nutritive value in forage grasses


Mace, W. J., Lunn, K., & Lloyd-West, C. (2014). Variation in the expression of ergot alkaloids between individual tillers of perennial ryegrass. [Original Research]. Frontiers in Chemistry, 2. doi: 10.3389/fchem.2014.00107

Combs, M. D. A., Rendell, D., Reed, K. F. M., Mace, W. J., & Quinn, J. C. (2014). Evidence of dehydration and electrolyte disturbances in cases of perennial ryegrass toxicosis in Australian sheep. Australian Veterinary Journal, 92(4), 107-113. doi: 10.1111/avj.12161

Bylin, A. G., Hume, D. E., Card, S. D., Mace, W. J., Lloyd-West, C. M., & Huss-Danell, K. (2014). Influence of nitrogen fertilization on growth and loline alkaloid production of meadow fescue (Festuca pratensis) associated with the fungal symbiont Neotyphodium uncinatum. Botany, 92(5), 370-376. doi: 10.1139/cjb-2013-0253

Schardl, C. L., Young, C. A., Hesse, U., Amyotte, S. G., Andreeva, K., Calie, P. J., . . . Zeng, Z. (2013). Plant-Symbiotic Fungi as Chemical Engineers: Multi-Genome Analysis of the Clavicipitaceae Reveals Dynamics of Alkaloid Loci. PLoS Genet, 9(2), e1003323. doi: 10.1371/journal.pgen.1003323

Meale, S. J., Chaves, A. V., Hannah, M. C., Williams, S. R. O., Hume, D. E., Mace, W. J., & Moate, P. J. (2013). Comparison of wild type, AR1 and AR37 endophyte infected perennial ryegrass on in vitro methanogenesis. Animal Feed Science and Technology, 180(1-4), 10-17. doi: http://dx.doi.org/10.1016/j.anifeedsci.2012.12.003

Rasmussen, S., Lane, G. A., Mace, W., Parsons, A. J., Fraser, K., & Xue, H. (2012). The use of genomics and metabolomics methods to quantify fungal endosymbionts and alkaloids in grasses. Methods in Molecular Biology, 860, 213-226.

Cosgrove, G. P., Muetzel, S., Skipp, R. A., & Mace, W. J. (2012). Effects of endophytic and saprophytic fungi on in vitro methanogenesis. New Zealand Journal of Agricultural Research, 55(3), 293-307. doi: 10.1080/00288233.2012.693106

Moate, P. J., Williams, S. R. O., Grainger, C., Hannah, M. C., Mapleson, D., Auldist, M. J., . . . Wales, W. J. (2012). Effects of wild-type, AR1 and AR37 endophyte-infected perennial ryegrass on dairy production in Victoria, Australia. Animal Production Science, 52(12), 1117-1130. doi: http://dx.doi.org/10.1071/AN12126

Baldauf, M. W., Mace, W. J., & Richmond, D. S. (2011). Endophyte-Mediated Resistance to Black Cutworm as a Function of Plant Cultivar and Endophyte Strain in Tall Fescue. Environmental Entomology, 40(3), 639-647. doi: 10.1603/en09227

Reed, K. F. M., Nie, Z. N., Walker, L. V., Mace, W. J., & Clark, S. G. (2011). Weather and pasture characteristics associated with outbreaks of perennial ryegrass toxicosis in southern Australia. Animal Production Science, 51(8), 738-752. doi: http://dx.doi.org/10.1071/AN11016

Koulman, A., Cao, M., Faville, M., Lane, G., Mace, W., & Rasmussen, S. (2009). Semi-quantitative and structural metabolic phenotyping by direct infusion ion trap mass spectrometry and its application in genetical metabolomics. Rapid Communications in Mass Spectrometry, 23(15), 2253-2263.