Read our Research

agresearch metabolomics research mass spectrometer meat

agresearch metabolomics infographic research papers

McKeen, S., Young, W., Mullaney, J., Fraser, K., McNabb, W.C., Roy, N.C. (2019) Infant complementary feeding of prebiotics for the microbiome and immunity. Nutrients DOI: 10.3390/nu11020364

Cabrera, D., Wolber, F.M., Dittmer, K., Rogers, C., Ridler, A., Aberdein, D., Parkinson, T., Chambers, P., Fraser, K., Roy, N.C., Kruger, M. (2018) Glucocorticoids affect bone mineral density and bone remodelling in OVX sheep: A pilot study. Bone Reports DOI: 10.1016/j.bonr.2018.11.001

Milan, A.M., Hodgkinson, A.J., Mitchell, S.M., Prodhan, U.K., Prosser, C.G., Carpenter, E.A., Fraser, K., Cameron-Smith, D. (2018) Digestive responses to fortified cow or goat dairy drinks: A randomised controlled trial. Nutrients DOI: 10.3390/nu10101492

Gerard, P., Schwendel, B.H., Fraser, K., Eden, T. (2018) Effect of narrow-leaved plantain cultivar on development of two geometrid pests, Scopula rubraria and Epyaxa rosearia. New Zealand Journal of Agricultural Research DOI: 10.1080/00288233.2017.1398763

Aidoud, N., Delplanque, B., Baudry, C., Garcia, C., Moyon, A., Balasse, L., Guillet, B., Antona, C., Darmaun, D., Fraser, K., Ndiaye, S., Leruyet, P., Martin, J.-C. (2018) A combination of lipidomics, MS imaging, and PET scan imaging reveals differences in cerebral activity in rat pups according to the lipid quality of infant formulas. FASEB Journal DOI: 10.1096/fj.201800034R

Bermingham, E.N., Reis, M.G., Subbaraj, A.K., Cameron-Smith, D., Fraser, K., Jonker, A., Craigie, C.R. (2018) Distribution of fatty acids and phospholipids in different table cuts and co-products from New Zealand pasture-fed Wagyu-dairy cross beef cattle. Meat Science DOI: 10.1016/j.meatsci.2018.02.012

Cabrera, D., Kruger, M., Wolber, F.M., Roy, N.C., Totman, J.J., Henry, C.J., Cameron-Smith, D., Fraser, K. (2018) Association of plasma lipids and polar metabolites with low bone mineral density in Singaporean-Chinese menopausal women: A pilot study. International Journal of Environmental Research and Public Health DOI: 10.3390/ijerph15051045

Matthews, Z.M., Edwards, P.J.B., Kahnt, A., Collett, M.G., Marshall, J.C., Partridge, A.C., Harrison, S.J., Fraser, K., Cao, M., Derrick, P.J. (2018) Serum metabolomics using ultra performance liquid chromatography coupled to mass spectrometry in lactating dairy cows following a single dose of sporidesmin DOI: 10.1007/s11306-018-1358-4

Gill, G.P., Bryant, C.J., Fokin, M., Huege, J., Fraser, K., Jones, C., Cao, M., Faville, M.J. (2018) Low pyrrolizidine alkaloid levels in perennial ryegrass is associated with the absence of a homospermidine synthase gene DOI: 10.1186/s12870-018-1269-6

Subbaraj, Arvind K., Kim, Yuan H. Brad, Fraser, Karl, & Farouk, Mustafa M. (2016). A hydrophilic interaction liquid chromatography-mass spectrometry (HILIC-MS) based metabolomics study on colour stability of ovine meat. Meat Science, 117, 163-172.

Samuelsson, Linda M., Young, Wayne, Fraser, Karl, Tannock, Gerald, Lee, Julian, & Roy, Nicole C. (2016). Digestive-resistant carbohydrates affect lipid metabolism in rats. Metabolomics, In Press.

Roche, Jessica, Love, Jonathan, Guo, Qianqian, Song, Jiancheng, Cao, Mingshu, Fraser, Karl, . . . Jameson, Paula E. (2016). Metabolic changes and associated cytokinin signals in response to nitrate assimilation in roots and shoots of Lolium perenne. Physiologia Plantarum, 156(4), 497-511. doi:10.1111/ppl.12412

Cao, Mingshu, Fraser, Karl, Huege, Jan, Featonby, Tom, Rasmussen, Susanne, & Jones, Chris. (2015). Predicting retention time in hydrophilic interaction liquid chromatography mass spectrometry and its use for peak annotation in metabolomics. Metabolomics, 11, 696-706. doi:10.1007/s11306-014-0727-x

Johnson, Richard D., Lane, Geoffrey A., Koulman, Albert, Cao, Mingshu, Fraser, Karl, Fleetwood, Damien J., . . . Johnson, Linda J. (2015). A novel family of cyclic oligopeptides derived from ribosomal peptide synthesis of an in planta-induced gene, gigA, in Epichloë endophytes of grasses. Fungal Genetics and Biology, 85, 14-24. doi:

Jones, Chris, Hatier, Jean-Hugues, Cao, Mingshu, Fraser, Karl, & Rasmussen, Susanne. (2015). Metabolomics of plant phosphorus-starvation response Annual Plant Reviews Volume 48 (pp. 215-236): John Wiley & Sons, Inc.

Leathwick, D. M., Miller, C. M., & Fraser, K. (2015). Selection for anthelmintic resistant Teladorsagia circumcincta in pre-weaned lambs by treating their dams with long-acting moxidectin injection. International Journal for Parasitology: Drugs and Drug Resistance, 5(3), 209-214. doi:

S. Wakelin, S. Harrison C. Mander B. Dignam S. Rasmussen S. Monk K. Fraser M. O’Callaghan. (2015). Impacts of endophyte infection of ryegrass on rhizosphere metabolome and microbial community. Crop and Pasture Science, 66, 1049-1057.

Subbaraj, Arvind K, Barrett, BrentA, Wakelin, SteveA, & Fraser, Karl. (2015). Using non-targeted direct analysis in real time-mass spectrometry (DART-MS) to discriminate seeds based on endogenous or exogenous chemicals. Analytical and Bioanalytical Chemistry, 407(25), 8047-8058. doi:10.1007/s00216-015-8977-7

Fraser, K., Lane, G. A., Otter, D. E., Hemar, Y., Quek, S.-Y., Harrison, S. J. and Rasmussen, S. (2014). Non-targeted analysis by LC-MS of major metabolite changes during the oolong tea manufacturing in New Zealand. Food Chemistry. DOI: 10.1016/j.foodchem.2013.11.054

Fraser, K., Lane, G. A., Otter, D. E., Harrison, S. J., Quek, S.-Y., Hemar, Y., & Rasmussen, S. (2014). Monitoring tea fermentation/manufacturing by direct analysis in real time (DART) mass spectrometry. Food Chemistry. DOI: 10.1016/j.foodchem.2013.05.054

Cao, M., Fraser, K., Huege, J., Featonby, T., Rasmussen, S. and Jones, C. (2014). Predicting retention time in hydrophilic interaction liquid chromatography mass spectrometry and its use for peak annotation in metabolomics. Metabolomics. DOI: 10.1007/s11306-014-0727-x

Mackintosh C.G., Cowie C., Fraser K., Johnstone P. and Mason, P.C. (2014). Reduced efficacy of moxidectin and abamectin in young red deer (Cervus elaphus) after 20 years of moxidectin pour-on use on a New Zealand deer farm.Veterinary Parasitology. DOI: 10.1016/j.vetpar.2013.09.028

Cao, M., Fraser, K. and Rasmussen, S. (2013). Computational Analyses of Spectral Trees from Electrospray Multi-Stage Mass Spectrometry to Aid Metabolite Identification. Metabolites. DOI:10.3390/metabo3041036

Johnson, L.J., Koulman, A., Christensen, M., Lane, G.A., Fraser, K., Forester, N., Johnson, R.D., Bryan, G.T. and Rasmussen, S. (2013). An Extracellular Siderophore Is Required to Maintain the Mutualistic Interaction of Epichloë festucae with Lolium perenne. PLoS Pathogens. DOI: 10.1371/journal.ppat.1003332

Fraser, K., Harrison, S.J., Lane, G.A., Otter, D.E., Hemar, Y., Quek, S.-Y. and Rasmussen, S. (2013). Analysis of low molecular weight metabolites in tea using mass spectrometry-based analytical methods. Critical Reviews in Food Science and Nutrition. DOI:10.1080/10408398.2011.619670.

Fraser, K., Lane, G. A., Otter, D. E., Hemar, Y., Quek, S-Y., Harrison, S. J. and Rasmussen, S. (2012). Analysis of metabolic markers of tea origin by UHPLC and high resolution mass spectrometry. Food Research International. DOI: 10.1016/j.foodres.2012.10.015.

Harrison, S., Xue, H., Lane, G., Jones, C., Villas-Boas, S. and Rasmussen, S. (2012). Investigating neoinulin biosynthesis using recombinant enzymes, isotopic labeling and multistage mass spectrometry on a linear ion trap to discern oligosaccharide fragmentations and structure. Biomacromolecules (submitted).

Rasmussen, S., Parsons, A. and Jones C. (2012). Metabolomics of Forage Plants - A Review. Annals of Botany, 110: 1281-1290.

Rasmussen, S., Lane, G.A., Mace, W., Parsons, A.J. Fraser, K., and Xue, H. (2012). The use of genomics and metabolomics methods to quantify fungal endosymbionts and alkaloids in grasses. In Hardy, N., Hall, R. (eds.) Plant Metabolomics: Methods and Protocols, Methods in Molecular Biology, 860: 213 - 226. Springer Science+Business Media, LLC.

Fraser, K., Harrison, S.J., Lane, G.A., Otter, D.E., Hemar, Y., Quek, S.-Y. and Rasmussen, S. (2012). HPLC MS/MS profiling of proanthocyanidins in teas: a comparative study. Journal of Food Composition and Analysis. 26: 43-51.

Fraser, K., Harrison, S.J., Lane, G., Otter, D.E., Hemar, Y., Quek, S.-Y., and Rasmussen S. (2012). Non-targeted analysis of tea by hydrophilic interaction liquid chromatography and high resolution mass spectrometry. Food Chemistry. 134: 1616-1623.

Harrison, S., Xue, H., Lane, G., Villas-Boas, S. and Rasmussen, S. (2012) Linear ion trap MSn of enzymatically synthesized 13C-labelled fructans reveals differentiating fragmentation patterns of β (1-2) and β (1-6) fructans and provides a tool for oligosaccharide identification in complex mixtures. Analytical Chemistry 84: 1540–1548.

Harrison, S., Fraser, K., Lane, G.A., Villas-Boas, S. and Rasmussen, S. (2012). Automated high-throughput analysis of fractions generated during the isolation of natural products. NZ Journal of Agricultural Research 55: 15-20.

Koulman, A., Lee, T.V., Fraser, K., Johnson, L., Arcus, V., Lott, S., Rasmussen, S. and Lane, G.A. (2012). Identification of extracellular siderophores and a related peptide from the endophytic fungus Epichloë festucae in culture and endophyte-infected Lolium perenne. Phytochemistry 75: 128-139.

Harrison, S., Fraser, K., Lane, G., Hughes, D., Villas-Boas, S. and Rasmussen, S. (2011). Analysis of High-Molecular-Weight Fructan Polymers in Crude Plant Extracts by High-Resolution LC-MS. Analytical and Bioanalytical Chemistry. 401: 2955-2963.

Draper, J., Rasmussen, S. and Zubair, H. (2011). Metabolite Analysis and Metabolomics in the Study of Biotrophic Interactions between Plants and Microbes, in Annual Plant Reviews Volume 43: Biology of Plant Metabolomics (ed R. D. Hall), Wiley-Blackwell, Oxford, UK.

Tibe, O. Meagher, L. P. Fraser, K. and Harding D. R. K. (2011). Condensed Tannins and Flavonoids from the Forage Legume Sulla (Hedysarum coronarium). Journal of Agricultural and Food Chemistry 59: 9402–9409.

Otter, D., Cao, M., Lin, H-M., Fraser, K., Edmunds, S., Lane, G. and Rowan D. (2011). Identification of Urinary Biomarkers of Colon Inflammation in IL10-/- Mice Using Short-Column LCMS Metabolomics. Journal of Biomedicine and Biotechnology, vol. 2011, Article ID 974701, 12 pages.

Rasmussen, S., Parsons, A.J., and Newman, J.A. (2009). Metabolomics Analysis of Lolium perenne – Neotyphodium lolii Symbiosis: More Than Just Alkaloids? Phytochemistry Reviews 8: 535-550.

Harrison, S.J., Fraser, K., Lane, G.A., Villas-Boas, S., and Rasmussen, S. (2009). A Reverse-Phase Liquid Chromatography/ Mass Spectrometry Method for the Analysis of High-Molecular-Weight Fructooligosaccharides. Analytical Biochemistry 395: 113-115.

Koulman, A., Lane, G.A., Harrison, S.J. and Volmer, D.A. (2009). From Differentiating Metabolites to Biomarkers. Analytical and Bioanalytical Chemistry 394: 663-670.

Koulman, A., Cao, M., Faville, M., Lane, G., Mace, W., and Rasmussen, S. (2009). Semi-Quantitative and Structural Metabolic Phenotyping by Direct Infusion Ion Trap Mass Spectrometry and its Application in Genetical Metabolomics. Rapid Communications in Mass Spectrometry 23: 2253-2263.

Rasmussen, S., Parsons, A.J., Fraser, K., Xue, H., and Newman, J.A. (2008). Metabolic Profiles of Lolium perenne are Differentially Affected by Nitrogen Supply, Carbohydrate Content and Fungal Endophyte Infection. Plant Physiology 146: 1440-1453.

Rasmussen, S., Parsons, A.J., Popay, A., Xue, H., and Newman, J.A. (2008). Plant-Endophyte-Herbivore Interactions: More Than Just Alkaloids? Plant Signaling & Behavior 3: 1-4.

Cao, M., Koulman, A., Johnson, L.J., Lane, G.A., and Rasmussen, S. (2008). Advanced Data-Mining Strategies for the Analysis of Metabolomic DIMSMS Data from the Association of Lolium perenne with its Endophytic Fungus Neotyphodium lolii. Plant Physiology 146: 1501-1514.

Koulman, A., Seeliger, C., Edwards, P.J.B., Fraser, K., Simpson, W., Johnson, L., Cao, M., Rasmussen S., and Lane, G.A. (2008). E/Z-Thesinine-O-4’-a-Rhamnoside, Pyrrolizidine Conjugates Produced by Grasses (Poaceae). Phytochemistry 69: 1927-1932.

Ryan, G., Parsons, A.J., Rasmussen, S., and Newman, J.A. (2008). Can Optimality Models and an ‘Optimality Research Program’ Help us Understand Some Plant-Fungal Relationships? Fungal Ecology 1: 115-123.

Rasmussen, S., Parsons, A.J., Bassett, S., Christensen, M.J., Hume, D.E., Johnson, L.J., Johnson, R.D., Simpson, W.R., Stacke, C., Voisey, C.R., Xue, H., and Newman, J.A. (2007). High Nitrogen Supply and Carbohydrate Content Reduce Fungal Endophyte and Alkaloid Concentration in Lolium perenne. New Phytologist 173: 787-797.

Koulman, A., Tapper, B.A., Fraser, K., Cao, M., Lane, G.A., and Rasmussen S. (2007). High-Throughput Direct Infusion Mass Spectrometry: A New Method for Metabolomics. Rapid Communications in Mass Spectrometry 21: 421-428.

Koulman, A., Lane, G.A., Christensen, M.J., Fraser, K. and Tapper, B.A. (2007). Peramine and Other Fungal Alkaloids Are Exuded in the Guttation Fluid of Endophyte-Infected Grasses. Phytochemistry 68: 355-360.

Villas-Boas, S.G., Rasmussen, S., and Lane, G.A. (2005). Metabolomics or Metabolite Profiles? Trends in Biotechnology 23: 385-386.

Rowan, D.D., Hunt, M.B., Cooney, J.M., Koulman, A., Rasmussen, S., and Lane, G.A. (2005). Plant Metabolomics: New Challenges for Chemists. Chemistry in NZ 69: 24-28.

Document Type

Nothing to display.